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Motherboards with 4 M.2 Slots

All motherboards

16 motherboards with 4 M.2 Slots from GIGABYTE and ASUS. Most cost $213 to $499, and half cost less than $273.

Top brands: GIGABYTE (8)ASUS (7)

GIGABYTESpec score 8.6

AM5, ATX, DDR5, 4 Memory slots

+Four M.2 slots for multiple storage drives
+Four DDR5 RAM slots for memory expansion
+Built-in Wi-Fi 7 for wireless connectivity
−2.5G LAN is slower than 5G LAN boards
$273.19-23%List: $354.99
as of 11/04/2026 15:08 PST - Details
ASUSSpec score 8.9

AM5, ATX, DDR5, 4 M.2 slots

+Wi-Fi 7: the highest wi-fi of the 18 here
+4 m.2 slots: the most m.2 slots of the 25 here
−2.5G: 13 of the 21 here have a higher wired lan
$229.99-12%List: $259.99
as of 11/04/2026 12:10 PST - Details
ASUSSpec score 9.5

AM5, ATX, DDR5, 4 M.2 slots

+Built-in Wi-Fi 7 for current wireless standards
+10G LAN for fast wired networking
+Four M.2 slots for storage expansion
−Limited to the AM5 socket
$499.99-9%List: $549.99
as of 11/04/2026 12:10 PST - Details
ASUSSpec score 8.9

AM5, ATX, DDR5, 4 M.2 slots

+AMD B850 chipset for AM5 Ryzen processors
+Four M.2 slots for multiple fast storage drives
+2.5G LAN for faster wired networking
−Full ATX size needs a large case
$199.99-5%Was: $209.99
as of 11/04/2026 12:10 PST - Details
ASUSSpec score 9.1

AM5, ATX, DDR5, 4 M.2 slots

+Wi-Fi 7: the highest wi-fi of the 18 here
+4 m.2 slots: the most m.2 slots of the 25 here
$455.32-5%List: $479.99
as of 11/04/2026 12:10 PST - Details
ASUSSpec score 9.5

AM5, ATX, DDR5, 4 M.2 slots

+AMD X870 chipset for AM5 Ryzen processors
+Four M.2 slots for multiple storage drives
+16+2+2 power stages for power delivery
−Full ATX size needs a large case
$285.47
as of 11/04/2026 12:10 PST - Details
GIGABYTESpec score 8.5

AM5, ATX, DDR5, 4 Memory slots

+Four M.2 slots for multiple storage drives
+Four DDR5 RAM slots for memory expansion
+Built-in Wi-Fi 7 for wireless connectivity
−Only one PCIe x16 slot limits multi-card setups
$499.99
as of 11/04/2026 15:08 PST - Details
GIGABYTESpec score 8.7

AM5, ATX, DDR5, 4 Memory slots

+Four M.2 sockets for storage expansion
+5G LAN for fast wired networking
+Built-in Wi-Fi 7 connectivity
$262.99
as of 11/04/2026 15:08 PST - Details
GIGABYTESpec score 8.7

AM5, ATX, DDR5, 4 Memory slots

+Wi-Fi 7: the highest wi-fi of the 18 here
+4 m.2 slots: the most m.2 slots of the 25 here
$255.99
as of 11/04/2026 15:08 PST - Details
GIGABYTESpec score 8.6

AM5, ATX, DDR5, 4 Memory slots

+Wi-Fi 7: the highest wi-fi of the 18 here
+4 m.2 slots: the most m.2 slots of the 25 here
−2.5G: 13 of the 21 here have a higher wired lan
$212.95
as of 11/04/2026 15:08 PST - Details
ASUSSpec score 9.5

AM5, mATX, DDR5, 4 M.2 slots

+Compact mATX form factor for smaller builds
+AMD B850 chipset for AM5 Ryzen processors
+Four M.2 slots for multiple storage drives
−Fewer expansion options than full ATX boards
$350.77
as of 11/04/2026 12:10 PST - Details
GIGABYTESpec score 9.2

sTR5, DDR5, 4 PCIe x16 slots, 4 M.2 slots

+sTR5 socket supports Threadripper PRO 7000 processors
+Four M.2 slots for extensive storage expansion
+Four PCIe x16 slots for multiple expansion cards
$1,042.01
as of 11/04/2026 15:08 PST - Details
NZXTSpec score 9.1

LGA1851, ATX, DDR5, 4 M.2 slots

+Four M.2 slots for fast storage
+Supports DDR5 memory
+Wi-Fi 7 support
No current price. Check it at the store.
GIGABYTESpec score 8.7

AM5, DDR5, 4 Memory slots, 4 M.2 slots

+Four M.2 sockets for storage expansion
+5G LAN for fast wired networking
+Built-in Wi-Fi 7 connectivity
No price recorded yet.
ASUSSpec score 8.9

AM5, mATX, DDR5, 4 M.2 slots

+Compact mATX form factor for smaller builds
+AMD B850 chipset for AM5 Ryzen processors
+Four M.2 slots for multiple storage drives
−Fewer expansion options than full ATX boards
$259.99
as of 11/04/2026 12:10 PST - Details
GIGABYTESpec score 8.7

AM5, DDR5, 4 Memory slots, 4 M.2 slots

+Four M.2 slots for multiple storage drives
+Four DDR5 RAM slots for memory expansion
+Built-in Wi-Fi 7 for wireless connectivity
No price recorded yet.

Compare specs

motherboardSocketForm factorMemory typeM.2 slotsWired LANSpec scorePrice
AM5ATXDDR542.5G8.6$273.19
as of 11/04/2026 15:08 PST - Details
AM5ATXDDR542.5G8.9$229.99
as of 11/04/2026 12:10 PST - Details
AM5ATXDDR5410G9.5$499.99
as of 11/04/2026 12:10 PST - Details
AM5ATXDDR542.5G8.9$199.99
as of 11/04/2026 12:10 PST - Details
AM5ATXDDR545G9.1$455.32
as of 11/04/2026 12:10 PST - Details
AM5ATXDDR549.5$285.47
as of 11/04/2026 12:10 PST - Details
AM5ATXDDR545G8.5$499.99
as of 11/04/2026 15:08 PST - Details
AM5ATXDDR545G8.7$262.99
as of 11/04/2026 15:08 PST - Details
AM5ATXDDR545G8.7$255.99
as of 11/04/2026 15:08 PST - Details
AM5ATXDDR542.5G8.6$212.95
as of 11/04/2026 15:08 PST - Details

Before you buy

Spec scores, pros and cons, and prices are explained in the How it works section of the About page.