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Motherboards with 16 Memory Slots

All motherboards

2 motherboards with 16 memory Slots. Prices run $1,103 to $1,196.

SupermicroSpec score 9.5

LGA4189, E-ATX, DDR4, 16 Memory slots

+Supports up to 4096 GB of DDR4 memory
+Sixteen RAM slots for large memory configurations
+Four M.2 slots for multiple fast storage drives
$1,103.20
as of 11/04/2026 07:10 PST - Details
SupermicroSpec score 9.3

LGA4710, DDR5, 16 Memory slots, 4TB

+Dual socket LGA4710 for two processors
+10G LAN for faster networking
+Supports up to 4TB of DDR5 memory
$1,196.99
as of 11/04/2026 07:10 PST - Details

Compare specs

motherboardSocketMemory typeMemory slotsMaximum memorySATA portsSpec scorePrice
LGA4189DDR4164TB9.5$1,103.20
as of 11/04/2026 07:10 PST - Details
LGA4710DDR5164TB109.3$1,196.99
as of 11/04/2026 07:10 PST - Details

Before you buy

Spec scores, pros and cons, and prices are explained in the How it works section of the About page.