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Motherboards with 4 PCIe x16 Slots

All motherboards

6 motherboards with 4 PCIe x16 Slots from Supermicro and ASRock Rack. Most cost $1,042 to $1,196, and half cost less than $1,091.

Top brands: Supermicro (4)

All filtersFilters (2)×
PCIe x16 slots: 4  ×ECC memory support: ECC memory support  ×Clear all
BrandSupermicro4GIGABYTE1Shangzhaoyuan1
SocketLGA46772LGA2011-31LGA41891LGA47101sTR51
Memory typeDDR54DDR42
Maximum memory4TB4256GB1
PCIe x16 slots46
M.2 slots2442
Wired LAN10G31G2
ECC memory supportECC memory support6
ChipsetAMD TRX501Intel C621A1Intel X991
PriceUnder $2001Under $1,2003$700 & above5$1,000 & above5
Clear allShow 6 motherboards
PCIe x16 slots: 4  ×ECC memory support: ECC memory support  ×6 resultsSort byRecommendedSpec scorePrice: low to highPrice: high to low
SupermicroSpec score 8.6

LGA4677, DDR5, 4TB, 4 PCIe x16 slots

+Supports up to 4096 GB of DDR5 memory
+Four PCIe x16 slots for multiple expansion cards
+ECC memory support for error-correcting RAM
−Only 1G LAN speed
$1,079.24
as of 11/04/2026 07:10 PST - Details
ShangzhaoyuanSpec score 8.1

LGA2011-3, E-ATX, DDR4, 256GB

+Dual CPU support for multi-processor workloads
+Supports up to 256GB of RAM
+Four PCIe x16 slots for multiple expansion cards
−Large E-ATX form factor needs a full-size case
−Uses the older LGA2011-3 socket
$184.99
as of 11/04/2026 07:07 PST - Details
GIGABYTESpec score 9.5

sTR5, DDR5, 4 PCIe x16 slots, 4 M.2 slots

+sTR5 socket supports Threadripper PRO 7000 processors
+Four M.2 slots for extensive storage expansion
+Four PCIe x16 slots for multiple expansion cards
$1,042.01
as of 11/03/2026 23:11 PST - Details
SupermicroSpec score 9.5

LGA4189, E-ATX, DDR4, 16 Memory slots

+Supports up to 4096 GB of DDR4 memory
+Sixteen RAM slots for large memory configurations
+Four M.2 slots for multiple fast storage drives
$1,103.20
as of 11/04/2026 07:10 PST - Details
SupermicroSpec score 9.2

LGA4710, DDR5, 16 Memory slots, 4TB

+Dual socket LGA4710 for two processors
+10G LAN for faster networking
+Supports up to 4TB of DDR5 memory
$1,196.99
as of 11/04/2026 07:10 PST - Details
SupermicroSpec score 9.2

LGA4677, DDR5, 4TB, 4 PCIe x16 slots

+10G LAN speed for fast networking
+Supports up to 4096 GB of DDR5 memory
+Four PCIe x16 slots for multiple expansion cards
$1,178.17
as of 11/04/2026 07:10 PST - Details

Compare specs

motherboardSocketForm factorMemory typeMaximum memoryPCIe x16 slotsSpec scorePrice
LGA4677DDR54TB48.6$1,079.24
as of 11/04/2026 07:10 PST - Details
LGA2011-3E-ATXDDR4256GB48.1$184.99
as of 11/04/2026 07:07 PST - Details
sTR5DDR549.5$1,042.01
as of 11/03/2026 23:11 PST - Details
LGA4189E-ATXDDR44TB49.5$1,103.20
as of 11/04/2026 07:10 PST - Details
LGA4710DDR54TB49.2$1,196.99
as of 11/04/2026 07:10 PST - Details
LGA4677DDR54TB49.2$1,178.17
as of 11/04/2026 07:10 PST - Details

Before you buy

Other PCIe x16 slots options

PC Cases264CPU Coolers393Processors247Data Center GPUs82Graphics Cards371Power Supplies237Memory374Storage Drives577Binoculars228Network Cables1,382Cameras2,556Chromebooks196

Popular filters

DDR4 Motherboards199DDR5 Motherboards190ATX Motherboards165mATX Motherboards152Motherboards under $200112Motherboards under $150109AM5 Motherboards99Motherboards with 4 Memory Slots96

Motherboards by use

Gaming Motherboards81LGA1700 DDR5 Motherboards47Budget Motherboards58Workstation Motherboards60

Related product types

Motherboards with 1 PCIe x16 Slot74Motherboards with 2 PCIe x16 Slots17

Spec scores, pros and cons, and prices are explained in the How it works section of the About page.