Motherboards with 4 PCIe x16 Slots

5 motherboards with 4 PCIe x16 Slots from Supermicro and ASRock Rack. Prices run $185 to $1,103.

ShangzhaoyuanSpec score 8.1

LGA2011-3, E-ATX, DDR4, 256GB

+Dual CPU support for multi-processor workloads

+Supports up to 256GB of RAM

+Four PCIe x16 slots for multiple expansion cards

−Large E-ATX form factor needs a full-size case

−Uses the older LGA2011-3 socket

$184.99

as of 11/04/2026 07:07 PST - Details

SupermicroSpec score 9.5

LGA4189, E-ATX, DDR4, 16 Memory slots

+Supports up to 4096 GB of DDR4 memory

+Sixteen RAM slots for large memory configurations

+Four M.2 slots for multiple fast storage drives

$1,103.20

as of 11/04/2026 07:10 PST - Details

ASRock RackSpec score 8.9

LGA4189, mATX, DDR4, 8 Memory slots

+Eight DDR4 memory slots for large capacity

+Four PCIe x16 slots for expansion cards

+10G LAN for high-speed networking

$791.21

as of 11/04/2026 12:09 PST - Details

ASRock Rack

LGA4189, ATX, DDR4, 8 Memory slots

+Eight DDR4 memory slots for large capacity

+13 SATA ports for many storage drives

+Four PCIe x16 slots for expansion cards

No price recorded yet.

MachinistSpec score 8.3

LGA2011-3, E-ATX, DDR4, 256GB

+4 pcie x16 slots: the most pcie x16 slots of the 9 here

−256GB maximum memory: 4 of the 6 here have a higher maximum memory

$195.99

as of 11/04/2026 17:09 PST - Details

Compare specs

Socket	Form factor	Memory type	Maximum memory	PCIe x16 slots	Spec score	Price
LGA2011-3	E-ATX	DDR4	256GB	4	8.1	$184.99 as of 11/04/2026 07:07 PST - Details
LGA4189	E-ATX	DDR4	4TB	4	9.5	$1,103.20 as of 11/04/2026 07:10 PST - Details
LGA4189	mATX	DDR4		4	8.9	$791.21 as of 11/04/2026 12:09 PST - Details
LGA4189	ATX	DDR4		4	n/a	No current price
LGA2011-3	E-ATX	DDR4	256GB	4	8.3	$195.99 as of 11/04/2026 17:09 PST - Details

Spec scores, pros and cons, and prices are explained in the How it works section of the About page.