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Desktop PCs for AI and Machine Learning

All desktops

6 desktop PCs for AI and machine learning from Adamant Custom, Skytech Gaming, Empowered PC and more. Prices run $3,720 to $4,729.

Desktops whose listing states a graphics card with 16GB of memory or more, which is what decides the size of model that fits on the machine.

We do not pick by hand: a desktop is here because its listed specs pass the checks.

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CPU: AMD Ryzen 9 9900X  ×Clear all
BrandMSI6
CPUAMD Ryzen 9 9950X3D18AMD Ryzen 7 9800X3D15AMD Ryzen 9 9950X15Intel Core Ultra 9 285K15AMD Ryzen Threadripper 9970X11AMD Ryzen 7 7800X3D8AMD Ryzen Threadripper 9980X8AMD Ryzen Threadripper PRO 9975WX8AMD Ryzen 9 9900X6
Show all 33AMD Ryzen Threadripper PRO 9985WX8Intel Core Ultra 7 270K8AMD Ryzen Threadripper PRO 9965WX6Intel Core Ultra 9 2856AMD Ryzen 7 9700X5AMD Ryzen 7 9850X3D5AMD Ryzen Threadripper 9960X4AMD Ryzen 7 8700F3AMD Ryzen 5 9600X2AMD Ryzen 9 9900X3D2AMD Ryzen Threadripper PRO 7985WX2Intel Core Ultra 72Intel Core Ultra 7 265F2AMD Ryzen 5 36001AMD Ryzen Threadripper PRO 7965WX1AMD Ryzen Threadripper PRO 9995WX1Intel Core i5-14400F1Intel Core i7-13700K1Intel Core i7-14700F1Intel Core i9-14900K1Intel Core i9-14900KF1Intel Core Ultra 5 250K1Intel Core Ultra 7 2651Intel Core Ultra 7 265KF1
GPUGeForce RTX 50806
GPU memory16GB6
RAM32GB364GB216GB1
Storage2TB55TB1
Operating systemWindows 11 Pro3Windows 11 Home2Windows 111
GPU modelRTX 50806
Dedicated graphics cardDedicated graphics card6
RAM typeDDR55
Wi-FiWi-Fi6
Price$3,000 & above3
Clear allShow 6 desktops
CPU: AMD Ryzen 9 9900X  ×6 resultsSort byRecommendedSpec scorePrice: low to highPrice: high to low
MSISpec score 7.3

AMD Ryzen 9 9900X, GeForce RTX 5080, 16GB Graphics, 32GB RAM

+Ryzen 9 9900X processor for demanding multitasking workloads
+GeForce RTX 5080 with 16GB graphics memory
+32GB DDR5 memory for smooth heavy applications
−Discrete graphics card adds to power demands
No current price. Check it at the store.
MSISpec score 7.5

AMD Ryzen 9 9900X, GeForce RTX 5080, 16GB Graphics, 64GB RAM

+Ryzen 9 9900X processor
+Discrete GeForce RTX 5080 with 16GB GDDR7 VRAM
+64GB DDR5 memory for heavy workloads
$4,729.00
as of 11/04/2026 18:06 PST - Details
MSISpec score 7.3

AMD Ryzen 9 9900X, GeForce RTX 5080, 16GB Graphics, 16GB RAM

−16GB ram: 161 of the 169 here have a higher ram
$3,879.00
as of 11/04/2026 18:06 PST - Details
MSISpec score 7.3

AMD Ryzen 9 9900X, GeForce RTX 5080, 16GB Graphics, 32GB RAM

+Discrete GeForce RTX 5080 with 16GB VRAM
+32GB RAM for multitasking
+2TB SSD storage
$3,720.00
as of 11/04/2026 18:06 PST - Details
MSISpec score 7.4

AMD Ryzen 9 9900X, GeForce RTX 5080, 16GB Graphics, 64GB RAM

+Ryzen 9 9900X 12-core processor for demanding multitasking
+GeForce RTX 5080 discrete graphics card
+64GB DDR5 memory for heavy multitasking
No price recorded yet.
MSISpec score 7.3

AMD Ryzen 9 9900X, GeForce RTX 5080, 16GB Graphics, 32GB RAM

−32GB ram: 107 of the 169 here have a higher ram
No price recorded yet.

Compare specs

desktopCPUGPUGPU memoryRAMStorageSpec scorePrice
AMD Ryzen 9 9900XGeForce RTX 508016GB32GB2TB7.3No current price
AMD Ryzen 9 9900XGeForce RTX 508016GB64GB5TB7.5$4,729.00
as of 11/04/2026 18:06 PST - Details
AMD Ryzen 9 9900XGeForce RTX 508016GB16GB2TB7.3$3,879.00
as of 11/04/2026 18:06 PST - Details
AMD Ryzen 9 9900XGeForce RTX 508016GB32GB2TB7.3$3,720.00
as of 11/04/2026 18:06 PST - Details
AMD Ryzen 9 9900XGeForce RTX 508016GB64GB2TB7.4No current price
AMD Ryzen 9 9900XGeForce RTX 508016GB32GB2TB7.3No current price

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Other uses

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Popular filters

Desktops with Wi-Fi603DDR5 Desktops589Desktops with Windows 11 Pro539Desktops with a Dedicated Graphics Card510Desktops with 1TB Storage431Desktops with 16GB RAM344Desktops with 32GB RAM318Desktops with Windows 11 Home287

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Prebuilt Gaming PCs239Prebuilt PCs for Video Editing250Workstation PCs268Business Desktop PCs335Desktop PCs for Home and Office279

Spec scores, pros and cons, and prices are explained in the How it works section of the About page.