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Desktop PCs for AI and Machine Learning

All desktops

8 desktop PCs for AI and machine learning from Adamant Custom, Skytech Gaming, Empowered PC and more. Price: $48,699.99.

Desktops whose listing states a graphics card with 16GB of memory or more, which is what decides the size of model that fits on the machine.

We do not pick by hand: a desktop is here because its listed specs pass the checks.

Adamant CustomSpec score 8.4

AMD Ryzen Threadripper 9980X, GeForce RTX 5090, 32GB Graphics, 512GB RAM

+64-core Threadripper 9980X for very heavy multi-threaded workloads
+512GB DDR5 memory for very large datasets and projects
+32GB VRAM on RTX 5090 for demanding GPU workloads
−Liquid cooling adds pump and radiator maintenance
−Large 8TB storage footprint may increase case size
$48,699.99
as of 11/04/2026 12:06 PST - Details
Adamant CustomSpec score 7.6

AMD Ryzen Threadripper 9980X, RTX PRO 2000, 16GB Graphics, 256GB RAM

+256GB DDR5 RAM for memory-heavy workloads
+16GB GPU memory for graphics and AI tasks
+1TB storage for a moderate file library
−1TB storage is less than the other configurations
No price recorded yet.
Adamant CustomSpec score 7.5

AMD Ryzen Threadripper 9980X, RTX PRO 4000, 24GB Graphics, 32GB RAM

+4TB storage for large project libraries
+64-core Threadripper 9980X processor
+ECC memory for error-checked RAM
−Only 32GB RAM, the lowest in this lineup
No price recorded yet.
Adamant CustomSpec score 9.3

AMD Ryzen Threadripper 9980X, RTX PRO 6000, 96GB Graphics, 512GB RAM

+512GB DDR5 RAM with ECC for large in-memory datasets
+96GB GPU memory for large models and datasets
+8TB storage for large project libraries
No price recorded yet.
Adamant CustomSpec score 8.7

AMD Ryzen Threadripper 9980X, RTX PRO 6000, 96GB Graphics, 128GB RAM

+96GB GPU memory for large models and datasets
+8TB storage for large project libraries
+64-core Threadripper 9980X processor
No price recorded yet.
Adamant CustomSpec score 8.5

AMD Ryzen Threadripper 9980X, RTX PRO 5000, 48GB Graphics, 512GB RAM

+512GB DDR5 RAM for very large in-memory datasets
+48GB GPU memory for demanding graphics work
+2TB storage for a sizable file library
No price recorded yet.
Adamant CustomSpec score 9.1

AMD Ryzen Threadripper 9980X, RTX PRO 6000, 96GB Graphics, 512GB RAM

+64-core Threadripper 9980X processor for heavy parallel workloads
+512GB DDR5 memory for very large datasets
+RTX PRO 6000 with 96GB VRAM for very large graphics workloads
No price recorded yet.
Adamant CustomSpec score 8.3

AMD Ryzen Threadripper 9980X, GeForce RTX 5090, 32GB Graphics, 512GB RAM

+64-core Threadripper 9980X processor for heavy parallel workloads
+512GB DDR5 memory for very large datasets
+GeForce RTX 5090 with 32GB VRAM for demanding graphics work
No price recorded yet.

Compare specs

desktopCPUGPUGPU memoryRAMStorageSpec scorePrice
AMD Ryzen Threadripper 9980XGeForce RTX 509032GB512GB8TB8.4$48,699.99
as of 11/04/2026 12:06 PST - Details
AMD Ryzen Threadripper 9980XRTX PRO 200016GB256GB1TB7.6No current price
AMD Ryzen Threadripper 9980XRTX PRO 400024GB32GB4TB7.5No current price
AMD Ryzen Threadripper 9980XRTX PRO 600096GB512GB8TB9.3No current price
AMD Ryzen Threadripper 9980XRTX PRO 600096GB128GB8TB8.7No current price
AMD Ryzen Threadripper 9980XRTX PRO 500048GB512GB2TB8.5No current price
AMD Ryzen Threadripper 9980XRTX PRO 600096GB512GB2TB9.1No current price
AMD Ryzen Threadripper 9980XGeForce RTX 509032GB512GB4TB8.3No current price

Before you buy

Spec scores, pros and cons, and prices are explained in the How it works section of the About page.