AMD Ryzen AI 9 HX 375, RTX 5080, 16GB Graphics, 64GB RAM
Laptops for AI and Data Science
6 laptops for AI and data science from EXCaliberPC, Lenovo, ASUS and more. Prices run $2,809 to $14,999.
Laptops whose listing states a graphics card with 12GB of memory or more, which is what decides the size of model that fits on the machine.
We do not pick by hand: a laptop is here because its listed specs pass the checks.
Spec score 8.2
+RTX 5080 with 16GB graphics memory
+240Hz refresh rate on a QHD+ IPS panel
+64GB DDR5 RAM for very heavy multitasking
−Windows 11 Home edition only
No price recorded yet.
Product details
HP OMEN Max 240Hz Ryzen AI 9 HX 375 RTX 5080 Gaming Laptop | 64GB DDR5, 2TB | 16" QHD+ IPS Display, Copilot +,No price recorded yet.View on Amazon
Spec score8.2
Pros
+RTX 5080 with 16GB graphics memory
+240Hz refresh rate on a QHD+ IPS panel
+64GB DDR5 RAM for very heavy multitasking
+2TB SSD storage for a large game library
Cons−Windows 11 Home edition only
Compared with the 6 laptops on this page+240 Hz screen: only 4 of 76 here refresh faster
+2.72 kg: 35 of the 66 here are heavier
−2TB storage: 35 of the 70 here have more
How pros and cons are picked (About: Disclaimer)About this product
Spec score 8.1
Intel Core Ultra 9 275HX, RTX 5080, 16GB Graphics, 32GB RAM
+18-inch 2.5K display with 240Hz refresh rate
+RTX 5080 with 16 GB VRAM for demanding games
+32 GB DDR5 RAM at 5600 MT/s
−Heavy at 3.42 kg for daily carrying
$3,799.99
as of 11/04/2026 12:21 PST - DetailsProduct details
ASUS ROG Strix G18 Gaming Laptop, Intel Ultra 9 275HX, NVIDIA RTX 5080 | 32GB DDR5 5600MT/s, 2TB SSD, 18" 2.5K 240Hz
$3,799.99as of 11/04/2026 12:21 PST - Details
View on AmazonSpec score8.1
Pros
+18-inch 2.5K display with 240Hz refresh rate
+RTX 5080 with 16 GB VRAM for demanding games
+32 GB DDR5 RAM at 5600 MT/s
+2 TB SSD for a large game library
Cons−Heavy at 3.42 kg for daily carrying
Compared with the 6 laptops on this page+240 Hz screen: only 4 of 76 here refresh faster
−3.42 kg: 47 of the 66 here are lighter
−2TB storage: 35 of the 70 here have more
How pros and cons are picked (About: Disclaimer)About this product
Spec score 8.5
Intel Core Ultra 9, RTX 5080, 16GB Graphics, 128GB RAM
+4K UHD Mini LED screen with 240Hz refresh rate
+128 GB DDR5 memory for heavy multitasking
+16 GB VRAM on the RTX 5080
−Heavy at 3.7 kg for daily carrying
$10,889.00
as of 11/04/2026 12:23 PST - DetailsProduct details
HIDevolution [2026] ASUS ROG Strix Scar 18 G835LWG 18" 4K 240Hz Mini LED, 2.7 GHz Ultra 9-290HX Plus, RTX 5080, 128 GB
$10,889.00as of 11/04/2026 12:23 PST - Details
View on AmazonSpec score8.5
Pros
+4K UHD Mini LED screen with 240Hz refresh rate
+128 GB DDR5 memory for heavy multitasking
+16 GB VRAM on the RTX 5080
+16 TB storage for a very large game library
Cons−Heavy at 3.7 kg for daily carrying
Compared with the 6 laptops on this page+16TB storage: none of the 70 here have more
+240 Hz screen: only 4 of 76 here refresh faster
−3.7 kg: 63 of the 66 here are lighter
How pros and cons are picked (About: Disclaimer)About this product
Spec score 8.5
Intel Core Ultra 9, RTX 5080, 16GB Graphics, 192GB RAM
+192GB DDR5 RAM for extremely heavy multitasking
+4K UHD display on a large 18-inch screen
+200Hz refresh rate for smooth visuals
−Heavy at 3.29 kg for daily carrying
$14,999.00
as of 11/04/2026 12:23 PST - DetailsProduct details
HIDevolution [2025] EVOC High Performance Systems X5801B (X580WNS-G) 18" UHD+ 200Hz, 2.1 GHz Ultra 9-275HX, RTX 5080,
$14,999.00as of 11/04/2026 12:23 PST - Details
View on AmazonSpec score8.5
Pros
+192GB DDR5 RAM for extremely heavy multitasking
+4K UHD display on a large 18-inch screen
+200Hz refresh rate for smooth visuals
+RTX 5080 GPU with 16GB VRAM for demanding work
Cons−Heavy at 3.29 kg for daily carrying
Compared with the 6 laptops on this page−3.29 kg: 46 of the 66 here are lighter
−200 Hz screen: 49 of the 76 here refresh faster
How pros and cons are picked (About: Disclaimer)About this product
Spec score 8.1
Intel Core Ultra 9, RTX 5080, 16GB Graphics, 32GB RAM
+16-inch WQXGA display with 240Hz refresh rate
+RTX 5080 with 16GB VRAM
+32GB DDR5 memory
$2,809.00
as of 11/04/2026 12:27 PST - DetailsProduct details
msi Vector 16 HX AI 400 Gaming Laptop, Intel Ultra 9-275HX, 32 GB DDR5 RAM, 1 TB PCIe SSD, 16" WQXGA (2560x1600) 240Hz
$2,809.00as of 11/04/2026 12:27 PST - Details
View on AmazonSpec score8.1
Pros
+16-inch WQXGA display with 240Hz refresh rate
+RTX 5080 with 16GB VRAM
+32GB DDR5 memory
+1TB PCIe SSD storage
Compared with the 6 laptops on this page+240 Hz screen: only 4 of 76 here refresh faster
+2.7 kg: 38 of the 66 here are heavier
−1TB storage: 60 of the 70 here have more
How pros and cons are picked (About: Disclaimer)About this product
Spec score 8.3
Intel Core Ultra 9, RTX 5080, 16GB Graphics, 128GB RAM
+16 TB storage for a very large library of files and games
+18-inch 4K UHD Mini LED screen
+128 GB DDR5 memory with 16 GB VRAM on the RTX 5080
−3.6 kg is heavy for daily carrying
No price recorded yet.
Product details
HIDevolution [2025] MSI Raider 18 HX AI A2XWIG 18" UHD+ 120Hz Mini LED, 2.1 GHz Ultra 9-285HX, RTX 5080, 128 GB DDR5No price recorded yet.View on Amazon
Spec score8.3
Pros
+16 TB storage for a very large library of files and games
+18-inch 4K UHD Mini LED screen
+128 GB DDR5 memory with 16 GB VRAM on the RTX 5080
+Lightweight for an 18-inch laptop at 3.6 kg
Cons−3.6 kg is heavy for daily carrying
Compared with the 6 laptops on this page+16TB storage: none of the 70 here have more
−3.6 kg: 53 of the 66 here are lighter
−120 Hz screen: 54 of the 76 here refresh faster
How pros and cons are picked (About: Disclaimer)About this product
Compare specs
| laptop | CPU | GPU | GPU memory | RAM | Storage | Spec score | Price |
|---|---|---|---|---|---|---|---|
| AMD Ryzen AI 9 HX 375 | RTX 5080 | 16GB | 64GB | 2TB | 8.2 | No current price | |
| Intel Core Ultra 9 275HX | RTX 5080 | 16GB | 32GB | 2TB | 8.1 | $3,799.99 as of 11/04/2026 12:21 PST - Details | |
| Intel Core Ultra 9 | RTX 5080 | 16GB | 128GB | 16TB | 8.5 | $10,889.00 as of 11/04/2026 12:23 PST - Details | |
| Intel Core Ultra 9 | RTX 5080 | 16GB | 192GB | 8.5 | $14,999.00 as of 11/04/2026 12:23 PST - Details | ||
| Intel Core Ultra 9 | RTX 5080 | 16GB | 32GB | 1TB | 8.1 | $2,809.00 as of 11/04/2026 12:27 PST - Details | |
| Intel Core Ultra 9 | RTX 5080 | 16GB | 128GB | 16TB | 8.3 | No current price |
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